Clinical Evidence

Endolift® for skin laxity of the lower face (Randomized Controlled Trial)

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Endolift® significantly improves lower-face skin laxity in controlled clinical trial

Authors & Journal: Leonardo Longo, Roberto Dell’Avanzato et al. — Laser Therapy (2022)

Study type: Randomized controlled trial

Patients: 96 subjects (ages 45–55)

Treatment area: Lower third of the face

Key results:

  • Significant improvement in facial skin laxity
  • Measurable tightening using standardized ptosis grading
  • Strong outcomes both with Endolift alone and combined photobiomodulation
  • Procedure performed without surgery

Clinical relevance: Demonstrates that Endolift® can produce measurable lifting and tightening effects in the lower face in a controlled clinical population.

Endolift® skin tightening: 11-year clinical experience

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11-year clinical experience confirms consistent Endolift® results in face and body lifting

Authors: Roberto Dell’Avanzato — clinical experience report

Study type: Long-term observational experience

Sample: 1000+ treated areas

Treatment areas: Face, Neck, Jawline, Abdomen, Arms

Key results:

Consistent improvement in:

  • Skin laxity
  • facial contour
  • submental definition


Clinical relevance: Provides long-term practitioner evidence supporting repeatable treatment outcomes.

Endolift® for facial rejuvenation with hybrid filler protocol

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Combined Endolift® laser and hybrid fillers improve submental fat and skin laxity

Authors & Journal: Proietti et al. — Dermatology Journal of Cosmetic and Laser Therapy (2023)

Study type: Prospective controlled case series

Patients: 7 subjects

Treatment area: Submental region

Key results:

  • Reduced submental fat
  • Improved skin elasticity
  • Reduced wrinkle severity
  • Effects maintained up to 12 months


Clinical relevance: Supports combined Endolift protocols for enhanced lower-face contouring.

Endolift® treatment for hypertrophic scars and keloids

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1470 nm Endolift® laser significantly reduces hypertrophic scars and keloids

Authors & Journal: Li et al. — Scientific Reports (Nature Research, 2020)

Study type: Prospective cohort study

Patients: 21 patients

Key results:

  • Scar thickness reduced by ~28%
  • Blood perfusion reduced by up to 29.6%
  • Vancouver Scar Scale improved by up to 42%
  • No adverse events reported


Clinical relevance: Demonstrates strong safety and effectiveness of Endolift-based laser treatment for scar remodelling.

Endolift® for acne scars

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Clinical evaluation shows improvement in acne scar texture after Endolift® treatment

Authors & Journal: Sitohang et al. — Journal of Applied Cosmetology (2023)

Study type: Evaluation study

Treatment area: Acne scars

Key results:

  • Improvement in cutaneous fibrosis and scar texture
  • Enhanced dermal remodeling effects
  • Demonstrated benefit for rolling scars


Clinical relevance: Shows Endolift® contributes to collagen remodeling in post-acne scarring.

Endolift® for cutaneous ptosis (skin sagging)

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Endolift® improves skin ptosis using targeted optical energy treatment

Authors & Journal: Markabayeva et al. — Journal of Applied Cosmetology (2023)

Study type: Evaluation study

Treatment area: General cutaneous laxity

Key results:

  • Improvement in skin tightening using 1470 nm wavelength
  • Demonstrated effectiveness in topical laser-based lifting
  • Non-surgical procedure


Clinical relevance: Supports Endolift as a treatment option for mild-to-moderate skin laxity.

Endolift® for forehead wrinkles and frown lines

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Clinical study confirms Endolift® improves forehead wrinkles and glabellar lines

Authors & Journal: Nilforoushzadeh et al. — Journal of Cosmetic Dermatology (2022)

Study type: Clinical interventional study

Treatment area: Forehead, Glabella (frown lines)

Key results:

  • Visible reduction in wrinkle depth
  • Improved skin texture and symmetry
  • Enhanced facial appearance linked to aging-related line reduction


Clinical relevance: Supports Endolift as an effective minimally invasive option for upper-face rejuvenation.

Endolift® lower eyelid tightening (case report)

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Lower eyelid tightening achieved without surgery using Endolift® laser

Authors & Journal: Dell’Avanzato — Laser Therapy (2022)

Study type: Case report

Treatment area: Lower eyelids

Key results:

  • Improvement in wrinkle score and elastosis at 6 months
  • Positive results on investigator and patient global aesthetic scales
  • No incisions required
  • Immediate return to daily activities


Clinical relevance: Shows Endolift can safely treat delicate periorbital skin with minimal downtime.

Endolift® for eyebrow position and upper-eyelid laxity

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Endolift® improves eyebrow elevation and upper-eyelid skin laxity

Authors & Journal: Lotfi et al. — Skin Research and Technology (2023)

Study type: Clinical pilot study

Patients: 9 subjects

Treatment area: Upper eyelids, Eyebrow position

Key results:

  • Measurable improvement in eyebrow height
  • Reduced upper-eyelid laxity after treatment
  • Improvements confirmed by blinded physician assessment


Clinical relevance: Supports Endolift as a non-surgical option for upper-eye rejuvenation.

Endolift® for hidradenitis suppurativa

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Interstitial Endolift® laser treatment evaluated for hidradenitis suppurativa lesions

Authors & Journal: Medhat et al. — Journal of Applied Cosmetology (2023)

Study type: Evaluation study

Treatment area: Inflammatory lesions associated with hidradenitis suppurativa

Key results:

  • Demonstrated therapeutic potential using 1470 nm laser delivery
  • Minimally invasive optical energy treatment approach


Clinical relevance: Suggests Endolift may support treatment of chronic inflammatory skin conditions.

Endolift® for progressive lipodystrophy

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Endolift® laser shows therapeutic potential for progressive lipodystrophy treatment

Authors & Journal: Sigova et al. — Journal of Applied Cosmetology (2023)

Study type: Case study

Treatment area: Localized fat loss disorders (progressive lipodystrophy)

Key results:

  • Demonstrated tissue remodeling response using 1470 nm wavelength
  • Optical energy delivery supported structural dermal improvement
  • Non-surgical treatment approach


Clinical relevance: Suggests Endolift may support restoration of tissue contour irregularities linked to fat redistribution conditions.

Non-surgical eyelid ptosis correction with Endolift®

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Endolift® improves eyelid ptosis using direct optical energy delivery

Authors & Journal: Sadoughifar et al. — Journal of Applied Cosmetology (2023)

Study type: Evaluation study

Treatment area: Upper eyelids

Key results:

  • Improved eyelid position without surgery
  • Enhanced skin tightening of palpebral tissue
  • Demonstrated minimally invasive correction of eyelid laxity


Clinical relevance: Supports Endolift® as a non-blepharoplasty alternative for mild–moderate eyelid ptosis.

Endolift® “lunch-time lifting” facial rejuvenation protocol

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Endolift® enables immediate lifting results with minimal downtime

Authors: Roberto Dell’Avanzato, Giulia Dell’Avanzato

Study type: Clinical technique report

Treatment areas: Mid-face, Jawline, Lower face, Neck

Key results:

  • Immediate visible lifting effect
  • Reproducible outcomes
  • Suitable outpatient procedure
  • Minimal recovery time

Clinical relevance: Introduced the concept of Endolift® as a fast, non-surgical alternative to facelift procedures.

Endolaser soft-lift for body contouring

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Endolaser soft-lift produces skin tightening and contour improvement without surgery

Authors & Journal: Scrimali et al. — European Journal of Aesthetic Medicine and Dermatology (2013)

Study type: Clinical perspective study

Treatment areas: Abdomen, Body contour zones, Skin laxity regions

Key results:

  • Photothermal stimulation improves dermal contraction
  • Skin retraction comparable to some surgical techniques
  • Reduced recovery time vs traditional procedures

Clinical relevance: Supports laser-assisted soft-lift techniques for minimally invasive body remodeling.

Endolaser soft-lift: from theory to practice

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1470 nm Endolaser technology enables deep tissue tightening with fewer complications than surgery

Authors & Journal: Scrimali & Lomeo — Aesthetic Medicine Journal (2015)

Study type: Clinical technical report

Treatment areas: Body contouring and dermal tightening

Key results:

  • Deep subdermal photothermal action improves skin retraction
  • Less pain than surgical alternatives
  • Shorter recovery time
  • Fewer scars and complications


Clinical relevance: Provides mechanistic support for laser-assisted lifting approaches underlying Endolift techniques.

Trusted By Industry Leaders

“
Endolift® has been the most versatile and most effective medical device in our practices since 2023. The client satisfaction rate is definitely the highest compared to other lasers or skin-tightening modalities.
Dr Kaveh Karandish

Founder, PCH MedSpa
(Corona Del Mar, California)

“

The precision of the Endolift® device allows for a sophisticated treatment of both delicate facial structures and body contours, delivering refined skin tightening and targeted fat reduction. It has become a defining element of our physician-led approach to advanced face and body rejuvenation.

Dr Aria Fazlinejad

Founder, Lumin Physical Aesthetics
(Las Vegas, Nevada)

“

I have had the Endolift® since January 2023. I still think it is a groundbreaking technology. The results can be pretty magical, and pretty much very close to surgery, without going under the knife.

Dr TJ Tsay

Founder, AgelessMD
(Tustin, California)

“

It’s probably one of the most economical devices I’ve purchased. It’s probably the easiest to learn, and I’ve gotten great results with it. In particular, I really like it for the jowling, and the heaviness that people get on their face.

Dr Scott Sanderson

Founder, ThriveMedSpa
(Honolulu, Hawaii) 

Your Patients are Ready. Are you?

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PLEASE, BE ADVISED THAT IF YOU ARE NOT A MEDICAL PROFESSIONAL REGISTERED WITH THE GMC OR GDC, DO NOT SUBMIT AN INQUIRY. WE ARE NOT OFFERING TRAINING TO NON-MEDICAL PERSONNEL.

 

TRAINING WILL BE PROVIDED FOLLOWING THE PURCHASE OF EUFOTON LASEMAR 1500

* We DO NOT offer training to NMC, HCPC, or GPhC professionals.

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The Endolift® procedure is a cutting-edge, medical-only non-surgical laser treatment renowned for its remarkable ability to firm and tone the skin, effectively reducing laxity by retracting excess skin. In cases where necessary, ENDOLIFT® is also employed for reducing excessive fat and reshaping the face. It is often referred to as the gold standard in non- invasive skin tightening technology.
Ideal candidates for Endolift® are individuals with mild to moderate skin laxity on the face or body. This treatment is suitable for all skin types!
Endolift® stands as a distinct technology, often hailed as the non-invasive gold standard for achieving effective and long-lasting facelifts (skin tightening). Thanks to its thin probe, it can also be effectively used for tasks like acne scar subcision and cellulite subcision, yielding exceptional results.
Endolift® boasts a unique pedigree, developed by a team of experts over two decades ago. Attempts to replicate our technology can be found in the market, but our Fibres and Lasemar1500 devices remain unmatched in terms of efficacy and quality.
During the Endolift® procedure, a remarkably thin fibre-optic laser probe is inserted under the skin without the need for incisions. The laser energy is then carefully delivered to the deeper layers of the skin, stimulating collagen production and tightening the tissues. This controlled laser energy application kickstarts the body's natural healing process, resulting in skin tightening and improved texture. Additionally, the doctor can adjust the power to deliver enough energy to destroy adipose fat cells when required, which are then naturally eliminated by the lymphatic system.
Endolift® is commonly employed to treat areas of the face and neck that exhibit signs of aging, such as sagging skin, wrinkles, and loss of elasticity. It's often used to target the jawline, cheeks, nasolabial folds (smile lines), and the neck. Furthermore, it has proven highly effective in reducing localized fat in areas like the belly, inner thighs, bingo wings, and love handles.
The procedure is virtually painless. Local anesthesia is typically administered to numb the treatment area, minimizing any discomfort. While some patients may experience mild discomfort or a sensation of warmth during the procedure, it's generally not described as painful.
Endolift® triggers the natural production of structural proteins like collagen and elastin, resulting in improved skin 'architecture.' Early signs of improvement can often be observed within 4-8 weeks, with the process continuing over time. The peak results are usually realized 9-12 months after the procedure.
Yes, ENDOLIFT® is an FDA-approved minimally invasive outpatient laser procedure used in interstitial (endo-tissutal) aesthetic medicine. The laser treatment employs the latest Eufoton® LASEmaR® 1500, certified and approved by the American FDA for laser-assisted liposuction.
One of the primary benefits of Endolift® is its minimal downtime. Patients may experience some mild swelling, redness, and bruising in the treated area, typically subsiding within a few days to a week. Most patients can resume their normal activities shortly after the procedure.
The longevity of Endolift® results can vary from person to person. However, effects generally persist for several months to a few years. Maintenance treatments may be recommended to sustain results over time.
Endolift® is a skill-based procedure, exclusively performed by qualified medical practitioners who have undergone specialized training.
Endolift® results are both immediate and long-lasting. Following the treatment, results will continue to develop over several months as additional collagen forms in the deeper layers of the skin. Typically, these results can endure for 2 to 3 years, with the option to repeat the treatment after a year if desired.
The Endolift® procedure is a cutting-edge, medical-only non-surgical laser treatment renowned for its remarkable ability to firm and tone the skin, effectively reducing laxity by retracting excess skin. In cases where necessary, ENDOLIFT® is also employed for reducing excessive fat and reshaping the face. It is often referred to as the gold standard in non- invasive skin tightening technology.
Ideal candidates for Endolift® are individuals with mild to moderate skin laxity on the face or body. This treatment is suitable for all skin types!
Endolift® stands as a distinct technology, often hailed as the non-invasive gold standard for achieving effective and long-lasting facelifts (skin tightening). Thanks to its thin probe, it can also be effectively used for tasks like acne scar subcision and cellulite subcision, yielding exceptional results.
Endolift® boasts a unique pedigree, developed by a team of experts over two decades ago. Attempts to replicate our technology can be found in the market, but our Fibres and Lasemar1500 devices remain unmatched in terms of efficacy and quality.
During the Endolift® procedure, a remarkably thin fibre-optic laser probe is inserted under the skin without the need for incisions. The laser energy is then carefully delivered to the deeper layers of the skin, stimulating collagen production and tightening the tissues. This controlled laser energy application kickstarts the body's natural healing process, resulting in skin tightening and improved texture. Additionally, the doctor can adjust the power to deliver enough energy to destroy adipose fat cells when required, which are then naturally eliminated by the lymphatic system.
Endolift® is commonly employed to treat areas of the face and neck that exhibit signs of aging, such as sagging skin, wrinkles, and loss of elasticity. It's often used to target the jawline, cheeks, nasolabial folds (smile lines), and the neck. Furthermore, it has proven highly effective in reducing localized fat in areas like the belly, inner thighs, bingo wings, and love handles.
The procedure is virtually painless. Local anesthesia is typically administered to numb the treatment area, minimizing any discomfort. While some patients may experience mild discomfort or a sensation of warmth during the procedure, it's generally not described as painful.
Endolift® triggers the natural production of structural proteins like collagen and elastin, resulting in improved skin 'architecture.' Early signs of improvement can often be observed within 4-8 weeks, with the process continuing over time. The peak results are usually realized 9-12 months after the procedure.
Yes, ENDOLIFT® is an FDA-approved minimally invasive outpatient laser procedure used in interstitial (endo-tissutal) aesthetic medicine. The laser treatment employs the latest Eufoton® LASEmaR® 1500, certified and approved by the American FDA for laser-assisted liposuction.
One of the primary benefits of Endolift® is its minimal downtime. Patients may experience some mild swelling, redness, and bruising in the treated area, typically subsiding within a few days to a week. Most patients can resume their normal activities shortly after the procedure.
The longevity of Endolift® results can vary from person to person. However, effects generally persist for several months to a few years. Maintenance treatments may be recommended to sustain results over time.
Endolift® is a skill-based procedure, exclusively performed by qualified medical practitioners who have undergone specialized training.
Endolift® results are both immediate and long-lasting. Following the treatment, results will continue to develop over several months as additional collagen forms in the deeper layers of the skin. Typically, these results can endure for 2 to 3 years, with the option to repeat the treatment after a year if desired.

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We will get back to you shortly

Please be advised we are offering training exclusively to our clients